Active Research Projects
Dendrites and axons show extraordinarily diverse forms and modes of patterning, with important implications for nervous system wiring and neuronal function. Our lab is interested in how neurons acquire their type-specific morphology and organization and how this organization underlies circuit function. To approach this problem, we use molecular, genetic, anatomical, and behavioral approaches to identify the mechanisms that sculpt somatosensory circuits during development.
How are dendritic territories and axon targets established? How do cell-cell interactions determine these morphologies? What are the cellular and molecular mechanisms of tiling and self-avoidance?
Current Biology dispatch written by Dr. Craig Montell gives perspective on our paper and companion paper from Dan Tracey's lab.
Sam presented an outstanding talk and defense on her work on somatosensory circuit development. Congratulations Sam!