Active Research Projects
Dendrites and axons show extraordinarily diverse forms, with important implications for nervous system wiring and neuronal function. Our lab is interested in how neurons acquire their morphology and how this organization underlies circuit function. To approach this problem, we use molecular, genetic, anatomical, and behavioral approaches to identify the mechanisms that sculpt somatosensory circuits during development.
How are dendritic territories and axon targets established? How do cell-cell interactions determine these morphologies?
Watch the Zuckerman Institute animation on Grace's chemotherapy-induced peripheral neuropathy study.
Great work Grace and ZI animation team!
Congrats to Grace and our uptown collaborators in the Bartolini lab on this exploration of neuropathy in fly and mammalian sensory neurons!