Research Projects

Building neurons and circuits

Dendrites and axons show extraordinarily diverse forms and modes of patterning, with important implications for nervous system wiring and neuronal function. Our lab is interested in how neurons acquire their type-specific morphology and organization and how this organization underlies circuit function. To approach this problem, we use molecular, genetic, anatomical, and behavioral approaches to identify the mechanisms that sculpt somatosensory circuits during development.

Cell-cell interactions in dendrite development

How are dendritic territories established?  How do cell-cell interactions determine where and how dendrites receive sensory or synaptic input?   What are the cellular and molecular mechanisms of tiling and self-avoidance?

Assembly of somatosensory circuitry

How is somatosensory information represented in the central nervous system?  What are the developmental mechanisms that generate somatosensory axon maps?

Contact Us

Join us

We welcome rotation students in the Neurobiology and Behavior, Integrated, Genetics and Development, and Biological Sciences graduate programs, and the MD-PhD program at Columbia.

We welcome motivated Columbia undergraduates to participate in mentored research.  Undergraduates with interests in nervous system development and behavior should contact Dr. Grueber to learn about research opportunities.